USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: Q07960 USC-OGP 2-DE database:  Q07960 Q07960 General information about the entry View entry in simple text format Entry name RHG01_HUMAN Primary accession number Q07960 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Rho GTPase-activating protein 1; AltName: Full=CDC42 GTPase-activating protein; AltName: Full=GTPase-activating protein rhoGAP; AltName: Full=Rho-related small GTPase protein activator; AltName: Full=Rho-type GTPase-activating protein 1; AltName: Full=p50-RhoGAP;. Gene name Name=ARHGAP1 Synonyms=CDC42GAP, RHOGAP1 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0372: pI=5.81; Mw=49010 Cross-references UniProtKB/Swiss-Prot Q07960; RHG01_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name RHG01_HUMAN Primary accession number Q07960 Secondary accession number(s) D3DQQ6 Sequence was last modified on  November 1, 1996 (version 1) Annotations were last modified on  March 15, 2017 (version 178) Name and origin of the protein Description RecName: Full=Rho GTPase-activating protein 1; AltName: Full=CDC42 GTPase-activating protein; AltName: Full=GTPase-activating protein rhoGAP; AltName: Full=Rho-related small GTPase protein activator; AltName: Full=Rho-type GTPase-activating protein 1; AltName: Full=p50-RhoGAP; Gene name Name=ARHGAP1 Synonyms=CDC42GAP, RHOGAP1 Encoded on Name=ARHGAP1; Synonyms=CDC42GAP, RHOGAP1 Keywords 3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; GTPase activation; Phosphoprotein; Polymorphism; Reference proteome; SH3-binding. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U02570; AAA16142.1; ALT_INIT; mRNA EMBL Z23024; CAA80560.1; -; mRNA EMBL CH471064; EAW67983.1; -; Genomic_DNA EMBL CH471064; EAW67984.1; -; Genomic_DNA EMBL BC018118; AAH18118.1; -; mRNA CCDS CCDS7922.1; -; . PIR A49678; A49678; . RefSeq NP_004299.1; NM_004308.3; . RefSeq XP_011518397.1; XM_011520095.1; . UniGene Hs.138860; -; . PDB 1AM4; X-ray; 2.70 A; A/B/C=233-431 PDB 1GRN; X-ray; 2.10 A; B=237-439 PDB 1OW3; X-ray; 1.80 A; A=198-439 PDB 1RGP; X-ray; 2.00 A; A=198-439 PDB 1TX4; X-ray; 1.65 A; A=234-431 PDB 2NGR; X-ray; 1.90 A; B=206-439 PDBsum 1AM4; -; . PDBsum 1GRN; -; . PDBsum 1OW3; -; . PDBsum 1RGP; -; . PDBsum 1TX4; -; . PDBsum 2NGR; -; . ProteinModelPortal Q07960; -; . SMR Q07960; -; . BioGrid 106885; 36; . DIP DIP-6081N; -; . IntAct Q07960; 15; . MINT MINT-5006067; -; . STRING 9606.ENSP00000310491; -; . iPTMnet Q07960; -; . PhosphoSitePlus Q07960; -; . SwissPalm Q07960; -; . DMDM 3024550; -; . OGP Q07960; -; . EPD Q07960; -; . MaxQB Q07960; -; . PaxDb Q07960; -; . PeptideAtlas Q07960; -; . PRIDE Q07960; -; . DNASU 392; -; . Ensembl ENST00000311956; ENSP00000310491; ENSG00000175220; . GeneID 392; -; . KEGG hsa:392; -; . UCSC uc001ndd.5; human; . CTD 392; -; . DisGeNET 392; -; . GeneCards ARHGAP1; -; . HGNC HGNC:673; ARHGAP1; . HPA HPA004689; -; . HPA HPA008285; -; . MIM 602732; gene; . neXtProt NX_Q07960; -; . OpenTargets ENSG00000175220; -; . PharmGKB PA24956; -; . eggNOG KOG4406; Eukaryota; . eggNOG ENOG410XR4J; LUCA; . GeneTree ENSGT00420000029688; -; . HOGENOM HOG000231442; -; . HOVERGEN HBG054433; -; . InParanoid Q07960; -; . KO K18470; -; . OMA LIYFHHG; -; . OrthoDB EOG091G07HT; -; . PhylomeDB Q07960; -; . TreeFam TF324164; -; . Reactome R-HSA-194840; Rho GTPase cycle; . ChiTaRS ARHGAP1; human; . EvolutionaryTrace Q07960; -; . GeneWiki ARHGAP1; -; . GenomeRNAi 392; -; . PRO PR:Q07960; -; . Proteomes UP000005640; Chromosome 11; . Bgee ENSG00000175220; -; . CleanEx HS_ARHGAP1; -; . ExpressionAtlas Q07960; baseline and differential; . Genevisible Q07960; HS; . GO GO:0005737; C:cytoplasm; IDA:BHF-UCL; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl; . GO GO:0045296; F:cadherin binding; IDA:BHF-UCL; . GO GO:0005096; F:GTPase activator activity; IDA:MGI; . GO GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc; . GO GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome; . GO GO:0007266; P:Rho protein signal transduction; TAS:ProtInc; . GO GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI; . Gene3D 1.10.555.10; -; 1; . Gene3D 3.40.525.10; -; 1; . InterPro IPR001251; CRAL-TRIO_dom; . InterPro IPR008936; Rho_GTPase_activation_prot; . InterPro IPR000198; RhoGAP_dom; . Pfam PF13716; CRAL_TRIO_2; 1; . Pfam PF00620; RhoGAP; 1; . SMART SM00324; RhoGAP; 1; . SMART SM00516; SEC14; 1; . SUPFAM SSF48350; SSF48350; 1; . SUPFAM SSF52087; SSF52087; 1; . PROSITE PS50191; CRAL_TRIO; 1; . PROSITE PS50238; RHOGAP; 1; .

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